Leiomyosarcoma

Navigate leiomyosarcoma with better information.

LMS Compass helps you understand what leiomyosarcoma is, find clinicians and centers with real sarcoma experience, and search active treatment trials — without piecing together dozens of disconnected websites.

Specialist guidance Active treatment trials Trusted national resources

A patient and an oncology specialist reviewing treatment information together on a tablet in a modern cancer center consultation room

01 · Understanding LMS

What is leiomyosarcoma?

Leiomyosarcoma (LMS) is a rare cancer that develops from smooth muscle cells. Because smooth muscle exists throughout the body, LMS can arise in several locations; it is most commonly seen in the uterus, abdomen, and pelvis.

LMS

A rare soft-tissue sarcoma

LMS belongs to the soft-tissue sarcoma family. Its rarity is one reason pathology review, treatment planning, and clinical-trial decisions benefit from clinicians who routinely manage sarcoma rather than seeing a case once every few years.

Read the NCI LMS overview ↗
Where it begins

Smooth muscle

These muscles work automatically in areas such as blood vessels and hollow organs.

Common sites

Uterus · abdomen · pelvis

LMS can also develop elsewhere, so tumor site and pathology matter.

Why expertise matters

Rare cancers require pattern recognition

A sarcoma team is accustomed to uncommon pathology, specialized surgery, systemic therapy, and research options.

02 · Specialist navigator

Find care built around sarcoma expertise.

With LMS, “cancer specialist” and “sarcoma specialist” are not always the same thing. Look for a clinician and center with meaningful sarcoma volume, sarcoma-focused pathology, multidisciplinary review, and familiarity with current LMS research.

Trusted directories

Start with established sarcoma resources

Before you schedule

Ask the center these four questions.

How many LMS patients do you treat?Is pathology reviewed by a sarcoma pathologist?Does a multidisciplinary sarcoma team review cases?Do you offer or refer to LMS clinical trials?
Read the full specialist guide
Live · ClinicalTrials.gov

Clinical Trial Finder

Search active leiomyosarcoma treatment studies in real time. Results come directly from the ClinicalTrials.gov API, filtered to interventional treatment studies that list leiomyosarcoma as a condition.

One tool: the top four fields pull live studies from ClinicalTrials.gov, the bottom four narrow the results below.

matching treatment studies

Open registry ↗

Requesting current leiomyosarcoma studies from ClinicalTrials.gov…

Live research tape

Currently enrolling LMS studies

Uterine LMSNon-uterine
ClinicalTrials.gov

Loading currently enrolling leiomyosarcoma studies…

Recruitment status and trial locations change over time.

Search ClinicalTrials.gov ↗